Molecular basis of inheritance



  • In case of VNTR, do all humans have same basic repeat in a particular loci but different number of repeats at that loci?

    For example, if the 1st loci of one person has 11 nucleotides in the basic repeat, and there are 100 repetitions & 2nd loci has 12 nucleotides in the basic repeat, and there are 105 repetitions, is it necessary that each human in this world will have:

    a. 1st loci: 11 nucleotides in the basic repeat
    b. 2nd loci: 12 nucleotides in the basic repeat
    Only the number of repeats will vary in each human?

    Or is the sequence in basic repeat different for every human in a particular loci in VNTR? Please explain.



  • @anag
    The sequence presence is a VNTR because one individual has five repeats, while the other has seven repeats (number of repeats varies in different individuals). Each repeat is ten nucleotides, making it a minisatellite, rather than a microsatellite in which each repeat is 2-5 nucleotides.



  • @sunitasaxena So the number of repeats at a particular loci varies in each person but the number of nucleotides in the basic repeat at that loci is same?



  • @anag
    Yes


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