Ans given b
@samanta_isika The keto group will get reduced to the methyl group by Wolff kishner reduction
@jai-d-gr8 why can we not use clemmensen reduction here?
Sanket Biradar last edited by
HCl would react acid base with OH in reactant
@samanta_isika Clemensons Reduction works best for aromatic ketones; non-aromatic ketones, not so much. The mechanism has not been thoroughly worked out; it’s thought to occur through a series of one-electron transfers from zinc amalgam.
Why Would You Prefer The Wolff-Kishner Over the Clemmensen?
It’s somewhat rare to encounter conditions in an introductory class where a Wolff Kishner would be called for over a Clemmensen, or vice versa, but here are some things to think about.
The Wolff-Kishner is done under strongly basic conditions using high heat in a polar protic solvent.
The Clemmensen is performed in strongly acidic conditions. If you have a protecting group somewhere which can be removed with acid, such as an acetal or silyl ether, consider an alternative.